Tornado™ DNAse (RNase-free) is an endonuclease that digests ssDNA, dsDNA and DNA in DNA-RNA complexes. The enzyme contains an additional domain responsible for the effective binding of a substrate DNA. The result is a versatile nuclease that possesses remarkably higher affinity towards dsDNA, even in the nM range of the DNA concentration.
- removal of contaminating genomic DNA from RNA samples
- removal DNA matrix post in vitro transcription.
- study of DNA-protein interactions by DNase I footprinting
- preventing false positive PCR results in one-step RT-qPCR